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The structure of the rat trypsin-BPTI complex. The structure of rat trypsinogen has not been solved. Nevertheless, several lines of experimentation suggest that the activation domain of rat trypsinogen is disordered as observed in bovine trypsinogen (Pasternak et al. 1999). The four segments of the activation domain that are disordered in bovine trypsinogen (and presumably in rat trypsinogen) are shown in dark gray.
