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Structure of the ΔI16V17/D194N trypsinogen-BPTI (light bonds) and trypsin-BPTI complexes (dark bonds). Electron density is from a 2Fo-Fc map drawn at a contour level of 1.0 σ. The psi angle of Trp141 is rotated approximately 180° from its position in trypsin. The hydrogen bond (2.9 Å) between the carbonyl oxygen of Trp141 and the ND2 nitrogen of Asn194 is shown by the dotted lines.
