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. 2001 Jul;10(7):1426–1433. doi: 10.1110/ps.48801

Table 1.

Catalytic parameters Km(μM), kcat(s−1) and specificity constant (M−1s−1) of Leishmania major dUTPase for different nucleoside triphosphates and UTP

Substrate Km kcat kcat/Km
dUTP 2.11 49 2.3 × 107
dATP 1034 5.4 5.1 × 103
dTTP 1514 8.6 5.5 × 103
dGTP > 2000 6.4 6.4 × 103
dCTP > 2500 13 5.0 × 103
UTP > 2500 <0.5 < 2 × 103