Fig. 3.

Distribution of threading significance scores for the S. cerevisiae genome sequences. More significant scores are more negative. The three plots are distributions of different threading scoring functions: (A) sq, or sequence-sequence method; (B) br, or sequence-structure method; and (C) tt, structure-predicted structure method. These scoring methods are detailed in Jaroszewski et al. (1998). (Black bars) Threading scores for sequences in which a disulfide oxidoreductase active site was identified in the threading model. (FFF) fuzzy functional form.