Figure 2.

Examples of hybridization experiments on macaque (MMU) and human (HSA) with BAC clones in the breakpoint regions. (a) FISH results for the PBR: under the chromosomes are reported the letter codes assigned to each BAC as reported in Additional data file 1 and Figure 1. BACs that yielded single signal both on MMU and HSA are listed in white, duplicated clones in MMU and HSA are listed in red, and duplicated BACs but with a different pattern of hybridization are listed in yellow. (b) Results for the distal breakpoint region (DBR). (c) Examples of hybridization on MMU and HSA with specific macaque BAC clones obtained by library screening or by in silico analyses (for detail see the text) for both the PBR and DBR.