Table 2.
Amino acids significantly preferred (-) or avoided (+) at 5' ends of exons across species
| Amino acids*† | |||||||||||||||||||||||
| A | C | D | E | F | G | H | I | K | L4 | L2 | M | N | P | Q | R4 | R2 | S4 | S2 | T | V | W | Y | Species (number of exons)‡ |
| +2 | -4 | -5 | +7 | -3 | -1 | -2 | -8 | -6 | +1 | +4 | +3 | -7 | +5 | +6 | Human (178,438) | ||||||||
| +2 | -4 | -5 | +7 | -3 | -1 | -2 | -7 | -6 | +1 | +4 | +3 | +5 | +6 | Mouse (126,268) | |||||||||
| -2 | -1 | +2 | +3 | +1 | +5 | +4 | -3 | D. rerio (41,264) | |||||||||||||||
| -3 | +2 | +4 | +1 | +5 | -1 | +3 | -2 | -4 | -5 | C. elegans (79,958) | |||||||||||||
| -5 | +4 | +3 | -2 | +2 | +5 | -1 | +1 | -3 | -4 | -6 | C. briggsae (74,178) | ||||||||||||
| -1 | A. gambiae (7,930) | ||||||||||||||||||||||
| +1 | +3 | -1 | -3 | +2 | -2 | -4 | D. melanogaster (48,933) | ||||||||||||||||
| +1 | -3 | -2 | +4 | -1 | -4 | +3 | +2 | -5 | -6 | A. mellifera (45,426) | |||||||||||||
| +1 | +3 | +2 | A. thaliana (109,900) | ||||||||||||||||||||
| S. pombe (2,403) | |||||||||||||||||||||||
| S. cerevisiae (417) | |||||||||||||||||||||||
*Indices signify rank order of slope coefficients, separately for negative and positive trends. †L2, R2, S2 and L4, R4, S4 signify the two-fold and four-fold degenerate blocks of leucine, arginine, and serine, respectively. ‡S. cerevisiae terminal exons were retained given the small number of genes with more than one intron (eight).