Table 1.
Oligonucleotides and short repeats found in the local context of genomic HNF4α sites
Oligonucleotide/repeat | Mode | Wind_from | Wind_to | r min | r max | Alpha | Avrfreq_Y | Avrfreq_N |
MDDR | (I) | 22 | 66 | 0 | 0 | 0.003082 | 13.433 (3.665) | 11.051 (4.782) |
ANGB | (I) | 20 | 38 | 0 | 0 | 0.016132 | 5.358 (2.529) | 3.582 (2.845) |
CDDM | (I) | 36 | 38 | 0 | 0 | 0.020372 | 4.346 (2.332) | 3.212 (1.732) |
AV-VS | (II) | 1 | 34 | 33 | 33 | 0.008246 | 6.694 (3.663) | 4.893 (3.088) |
MD-DB | (II) | 20 | 70 | 20 | 25 | -0.003212 | 16.941 (3.078) | 14.711 (3.344) |
BR-NT | (II) | 33 | 37 | 9 | 18 | -0.003942 | 4.802 (5.460) | 7.702 (5.144) |
VS-YA | (II) | 1 | 34 | 11 | 11 | 0.0103 | 4.237 (1.742) | 3.121 (2.640) |
VB-HA | (II) | 1 | 34 | 5 | 5 | 0.008647 | 9.028 (2.985) | 6.517 (3.741) |
HM-GN | (II) | 40 | 50 | 2 | 4 | 0.006468 | 7.783 (4.335) | 4.672 (3.764) |
(RBNH)2 | (III) | 20 | 51 | 5 | 12 | 0.030376 | 7.259 (1.778) | 5.961 (2.168) |
(MVKN)2 | (III) | 20 | 51 | 7 | 13 | 0.015979 | 3.123 (1.413) | 2.388 (1.155) |
(BNDK)2 | (III) | 32 | 32 | 7 | 7 | -0.002214 | 0.000 (0.000) | 14.343 (28.652) |
(DNCD)2 | (III) | 28 | 42 | 7 | 7 | 0.068635 | 4.176 (2.797) | 1.051 (2.196) |
(NBHV)2 | (III) | 26 | 26 | 7 | 7 | -0.001045 | 0.000 (0.000) | 13.626 (28.102) |
(NVYB)2 | (III) | 29 | 29 | 7 | 7 | -0.001696 | 0.000 (0.100000) | 12.909 (27.523) |
Mode: (I), search for oligonucleotides; (II), dinucleotide pairs; (III), four-nucleotide repeats. Wind_from and Wind_to, sequence window in which the motif was found (the HNF4α site is located between positions 29 and 42, flanks are 28 bp and 33 bp long, respectively). rmin and rmax, distances between dinucleotide pairs and repeats. Alpha, coefficients in the linear function. Avrfreq_Y, the average frequency of the oligonucleotides in the corresponding window among sequences of the real sites. Avrfreq_N, background sequences. The standard error is given in parentheses.