Overview of mitochondria-related processes. A schematic cross-section of a mitochondrion is shown, with the proteins and protein complexes that are involved in various cellular pathways and processes. Complexes I-IV are the complexes of the respiratory chain. AIF, apoptosis-inducing factor; Cyt c, cytochrome c; i-AAA and m-AAA, proteases of the AAA family in the intermembrane space and matrix, respectively; ISC, iron-sulfur cluster assembly complex; Mfn, mitofusin; TIM, translocase of the inner membrane; TOB, topogenesis of mitochondrial outer membrane β-barrel proteins; TOM, translocase of the outer membrane; VDAC, voltage-dependent anion channel; Opa1, Optic Atrophy 1.