Table 4.
Compound | ID50 (ng/mL)* | ||||||
---|---|---|---|---|---|---|---|
H226 | IGROV | MCF7 | EVSA-T | WIDR | M19 | A498 | |
PTX | <0.003 | 0.010 | <0.003 | <0.003 | <0.003 | <0.003 | <0.003 |
20a | 41 | 19 | 16 | 11 | 13 | 45 | 40 |
20b | 21 | 11 | 6.6 | 7.2 | 10 | 17 | 38 |
20c | 25 | 26 | 6.9 | 5.2 | 11 | 24 | 45 |
20d | 48 | 45 | >63 | >63 | 47 | 47 | >63 |
25 | 16 | 27 | 9.2 | 9.3 | 11 | 20 | >60 |
MCF-7, EVSA are breast carcinoma, WIDR are colon, IGROV are ovarian carcinoma, M19 are melanoma, A498 renal carcinoma, H226 non small cell lung carcinoma, cell lines