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. Author manuscript; available in PMC: 2008 Jun 1.
Published in final edited form as: Bioorg Med Chem. 2007 Mar 18;15(11):3597–3623. doi: 10.1016/j.bmc.2007.03.041

Table 6.

In vitro cytotoxicities of taxoid derivatives 43–46 and immunoconjugate 47

Taxoid IC50 (nM)
A431 A549
38 0.09 0.1
43 2.0 ND
46 3.0 0.9
45 0.5 0.8
44 >3.0 ND
47-KS78 1.5 ND