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. 2008 Apr 3;27(9):1321–1332. doi: 10.1038/emboj.2008.64

Figure 5.

Figure 5

Loss of function is due to the N-glycan at the interface between the VFTs. (A) Comparison of the IP production stimulated by the GB1ASA NXS/T and QXS/T mutants. (B) Similar comparison of IP stimulation for the GB2 mutants. Data are means±s.e. of at least three independent measurements. (C) Effect of CGP7930 on Ca2+ signals in cells expressing the indicated GB2 mutants. Data are means±s.e. of triplicates from a typical experiment.