Table 4.

Adjuvant chemotherapy studies with positive results

Study	Treatment	No. p	Sup %	p	Criticism
GITSG 1982	MeCCNU + 5FU	71		<0.03	Not reproduced in
	Control	71			VASOG y ECOG
Neri et al 2001	Epi + 5FU/LV	69	30	<0.01	?
	Control	68	13
Grau et al 1998	MMC	45	44	0.004	Small number of cases.
	MMC + tegafur	40	67		11 years conscription.
					No control group
Hagiwara et al 1992	IP carbon-absorbed	24	69		Small number of cases.
	cisplatin			<0.005	Australian study
	Control	25	27		negative.
Kim et al 1992	MMC + 5FU + AraC + OK432	74	45	<0.05	Small number of cases.
	Control	64	23		Not reproduced
Cirera et al 1999	MMC + tegafur	76	56	0.04	?
	Control	72	36

Abbreviations: FU, fluorouracil; LT, leucovorin; MMC, mitomycin.