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. 2007 Aug;3(4):563–567.

Table 5.

Studies of adjuvant radiochemotherapy

Study Treatment P Sup % p Criticism
Lim et al 2004 5FU/LV + RT 291 58 - Not comparative
D2 Surgery
Park et al 2003 5FU/LV + RT 261 60 - Not comparative
D2 Surgery
Macdonald et al 2001 5FU/LV + RT 281 50%* Low compliance with protocol
Control 41%* (64%)
INT-0116 D2 Surgery 17% abandoned due to toxicity
10% *3 35% revision of RT plan
D1 Surgery years 3 toxic deaths
36% Poor quality of surgery

Abbreviations: FU, fluorouracil; LT, leucovorin; RT, radiotherapy.