Table 5.
Studies of adjuvant radiochemotherapy
| Study | Treatment | P | Sup % | p | Criticism |
|---|---|---|---|---|---|
| Lim et al 2004 | 5FU/LV + RT | 291 | 58 | - | Not comparative |
| D2 Surgery | |||||
| Park et al 2003 | 5FU/LV + RT | 261 | 60 | - | Not comparative |
| D2 Surgery | |||||
| Macdonald et al 2001 | 5FU/LV + RT | 281 | 50%* | Low compliance with protocol | |
| Control | 41%* | (64%) | |||
| INT-0116 | D2 Surgery | 17% abandoned due to toxicity | |||
| 10% | *3 | 35% revision of RT plan | |||
| D1 Surgery | years | 3 toxic deaths | |||
| 36% | Poor quality of surgery |
Abbreviations: FU, fluorouracil; LT, leucovorin; RT, radiotherapy.