Table 6.
Study | P No. rel/(Total no.) | Treatment | Locoregional relapses | Relapse* predictors | p* |
---|---|---|---|---|---|
Schwarz et al 2002 | 35/(73) | Surgery R0D2 | 23% | N3 | 0.005 |
only local 6% | T3/T4 | 0.008 | |||
Cirera et al 1999 | 37/(76) | Surgery D2 + CT | 26% | – | – |
50/(72) | Surgery D2 | 33% | |||
Lim et al 2004 | 114/(291) | Surgery | 19% | N3 | <0.0001 |
D2 + CT + RT | only local 7% | T3/T4 | <0.0001 | ||
Park et al 2003 | 114/(261) | Surgery | 29% | III/IV (M0) | <0.001 |
D2 + CT + RT | |||||
Macdonald et al 2001 | 120(281) | 10% D2 Surgery | 19% | ||
+ CT + RT | – | **NS | |||
(INT-0116) | 177/(275) | 10% D2 Surgery | 29%** |
Abbreviations: CT, chemotherapy; RT, radiotherapy.