Table 3.

Randomized trials evaluating the efficacy of esomeprazole vs other PPIs in combined endoscopic and symptomatic maintenance of healed erosive GERD

Reference	Study design	Number of patients	PPIs compared	Maintenance rates at 6 months
Lauritsen et al 2003	Double-blind, randomized	1224	Eso20 vs lan15 od	83 % vs 74%, p < 0.0001
Labenz et al 2005a	Double-blind, randomized	2766	Eso20 vs panto20 od	87% vs 74.9%, p < 0.0001
Devault et al 2006	Double-blind, randomized	1026	Eso20 vs lan15 od	84.5% vs 75.9%, p < 0.0007

Notes:No randomized studies comparing esomeprazole with rabeprazole or omeprazole as to healing erosive GERD were found.

Abbreviations:Eso, esomeprazole; lan, lansoprazole; panto, pantoprazole; PPI, proton-pump inhibitor.