Table 4.

Pharmacokinetics of posaconazole

Variable	Value
Volume of distribution (L)	1774
Protein binding (%)	>98
Elimination	Via feces (77%)
	Via urine (1%)
Half-life (hours)	35 (20–66)
Metabolism	Biotranformation via UDG pathway

Derived from data of Herbrecht (2004).

Abbreviations: UDG, uridine diphosphate – glucoronosyltransferase