Table 4.

Drugs that should not be coadministered with TPV/r

Potential for serious and/or life theatening reactions
Antiarrhythmics	Amiodarone
	Bepridil
	Flecainide
	Propafenone
	Qunidine
Antihistamines	Astemizole
	Terfenadine
Ergot derviates	Dihydroergotamine
	Ergonovine
	Ergotamine
	Methylergonovine
GI motility agent	Cisapride
Neuroleptic	Piomizide
	Sertindole
Sedatives	Midazolam
	Triazolam
Risk of sub-therapeutic TPV/r levels
Antibiotics	Rifampicin
Herbal preparations	St John’s Wort
Increased risk of myopathy, including rhabdomyolysis
HMG-CoA reductase inhibitors	Lovastatin
	Simvastatin