Table 5.

Estimation of relative risk of reduction of disease-free survival in African-American and Latina women with breast cancer using multivariate analysis

	Relative risk	95% CI	P value
Tumor size (≥ 5 cm versus <5 cm)	2.1	1.4–4.0	0.03
Lymph node (positive versus negative)	2.2	1.0–4.8	0.05
ER/PR status (negative versus positive)	1.9	1.0–3.3	0.04
pAkt status (high versus low)	2.5	1.3–4.8	0.006
HER2/neu status (positive versus negative)	1.7	1.0–3.3	0.05
Age (<50 years versus ≥ 50 years)	0.9	0.5–1.7	0.54
Ethnicity (African-American versus Latina)	1.2	0.7–2.2	0.54

CI, confidence interval; ER/PR, estrogen receptor/progesterone receptor; HER2/neu positive, HER2/neu 3+ examined by immunohistochemistry (IHC); HER2/neu negative, HER2/neu 2+ and HER2/neu 1+/negative by IHC; pAkt high, the pAkt index level above median level (>36); pAkt low, the pAkt index level less than or equal to median level (≤36).