Table 5.

Associations between ERBB2 and AP-2α and/or YY1 levels (immunohistochemistry) in the FISH-negative group

		ERBB2 expression (percentage)
	n	0/1+		2+		3+		P value
AP-2α expression								<0.001
Low	18	14	(78)	4	(22)	0	(0)
High	16	2	(12)	11	(69)	3	(19)
YY1 expression								0.106
Low	16	10	(63)	6	(37)	0	(0)
High	18	6	(33)	9	(50)	3	(17)
Combination								0.015
AP-2α lo/YY1 lo	13	10	(77)	3	(23)	0	(0)
AP-2α lo/YY1 hi or AP-2α hi/YY1 lo	8	4	(50)	4	(50)	0	(0)
AP-2α hi/YY1 hi	13	2	(15)	8	(62)	3	(23)

AP-2α, activator protein 2 alpha; FISH, fluorescent in situ hybridization; hi, high expression; lo, low expression; YY1, Yin Yang 1.