Table 2.
Functional tests of candidate genes
| Line | Gene | Mean locomotor reactivity (± SE) | F1,112 | P value | Human ortholog |
| BG01127 | muscleblind | 21.63 ± 1.47 | 37.47 | < 0.0001 | MBLN1 |
| BG01259 | Ken and barbie | 23.43 ± 1.32 | 17.26 | < 0.0001 | N/A |
| BG01697 | CG33523 | 24.13 ± 1.30 | 22.08 | < 0.0001 | N/A |
| BG01761 | Amphiphysin | 26.80 ± 0.93 | 5.66 | 0.019 | AMPH |
| BG01863 | Cysteine string protein | 20.50 ± 1.54 | 46.97 | < 0.0001 | DNAJC5B |
| BG02106 | CG31145 | 26.40 ± 0.97 | 2.03 | 0.157 | FAM20A |
| BG02109 | tartan | 26.15 ± 0.92 | 1.16 | 0.096 | N/A |
| BG02121 | center divider | 26.80 ± 0.77 | 1.16 | 0.285 | N/A |
| BG02676 | CG10990 | 25.30 ± 1.20 | 16.86 | < 0.0001 | PDCD4 |
| BG02715 | nebbish | 25.25 ± 1.27 | 14.41 | < 0.0001 | KIF14 |
The mean locomotor reactivity of the Canton S B control strain is 28.50 ± 0.20 s. Bonferroni significance threshold = 0.005. Human orthologs have homology scores of > 0.93 and Bootstrap scores of > 93%. N/A, not applicable; SE, standard error.