Table 1.

Effect of different factors on the quantitative expression of target genes

	Before considering multi-regulators	Two-regulator motifs			Three-regulator motifs
Possible time delays from regulator(s) to target genes	+	+	+	+	+	+
Conversion efficiency (non-negative)		+	+	+	+	+
Possible opposite regulation between regulators			+	+	+	+
Possible time delays among regulators				+		+
Number of significantly correlated motifs (interactions)	231	35	48	179	75	272
Number of motifs (interactions)	6,105	544	544	544	161	161
Percentage	3.78%	6.43%	8.82%	32.9%	21.7%	67.1%

Plus signs indicate that the corresponding factor is considered in the corresponding case.