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. 2007 Sep 4;8(9):R183. doi: 10.1186/gb-2007-8-9-r183

Table 2.

Sixteen total gene functional groups identified by the Functional Classification Tool

Gene functional group no. Associated biology Group enrichment score
1 Chemokine/cytokine 3.37
2 Transcription regulation 2.89
3 Signal transduction/membrane receptors 2.68
4 Kinase activity 2.54
5 DNA damage/repair 2.23
6 Iron binding 2.05
7 RNA processing/splicing factors 1.81
8 Organic acid transport 1.71
9 Cation/ion transport 1.69
10 DNA metabolism/chromosome organization 1.53
11 Cellular macromolecule catabolism 1.41
12 Metalloprotease 1.34
13 Macrotubule 1.24
14 Protein localization/fusion 1.17
15 Amine metabolism 1.1
16 RAS small GTPase 1.03

The genes of demo list 2 were analyzed by the Functional Classification Tool. The major biology terms associated with each group are manually summarized based on gene-term enrichment buttons provided for each functional group.