Table 1.
| NORMAL BREAST | |||||||||||
| MOESIN | MEM | MEM | CYTO | P-MOESIN | MEM | MEM | CYTO | ||||
| CYTO | CYTO | ||||||||||
| 1 | INTENSE | x | INTENSE | x | |||||||
| 2 | INTENSE | x | INTENSE | x | |||||||
| 3 | INTENSE | x | INTENSE | x | |||||||
| 4 | INTENSE | x | INTENSE | x | |||||||
| 5 | INTENSE | x | INTENSE | x | |||||||
| FIBROADENOMAS | |||||||||||
| MOESIN | MEM | MEM | CYTO | P-MOESIN | MEM | MEM/CITO | CYTO | ||||
| CYTO | |||||||||||
| 6 | INTENSE | x | INTENSE | x | |||||||
| 7 | INTENSE | x | INTENSE | x | |||||||
| 8 | INTENSE | x | INTENSE | x | |||||||
| 9 | INTENSE | x | INTENSE | x | |||||||
| 10 | INTENSE | x | INTENSE | x | |||||||
| INV. DUCTAL CARCINOMAS | |||||||||||
| SIZE | pNx | ER% | MOESIN | MEM | MEM | CYTO | P-MOESIN | MEM | MEM | CYTO | |
| CYTO | CYTO | ||||||||||
| ER POS/LYMPH NODE POS | |||||||||||
| 11 | 18 mm | pN2a (7/16) | 84% | FOCAL | x | NEGATIVE | |||||
| 12 | 19 mm | pN1m (1/8) | 98% | INTENSE | x | INTENSE | x | ||||
| 13 | 15 mm | pN1a (1/3) | 98% | INTENSE | x | INTENSE | x | ||||
| 14 | 16 mm | pN1a (2/24) | 100% | INTENSE | x | FOCAL | x | ||||
| 15 | 16 mm | pN3a (8/15) | 95% | INTENSE | x | FOCAL | x | ||||
| ER POS/LYMPH NODE NEG | |||||||||||
| 16 | 14 mm | 90% | INTENSE | x | FOCAL | x | |||||
| 17 | 15 mm | 90% | INTENSE | x | INTENSE | x | |||||
| 18 | 10 mm | 100% | INTENSE | x | INTENSE | x | |||||
| 19 | 15 mm | 99% | FOCAL | x | INTENSE | x | |||||
| 20 | 18 mm | 98% | FOCAL | x | FOCAL | x | |||||
| ER NEG/LYMPH NODE POS | |||||||||||
| 21 | 18 mm | pN2a (7/16) | 0% | FOCAL | x | NEGATIVE | |||||
| 22 | 17 mm | pN1m (1/17) | 0% | INTENSE | x | INTENSE | x | ||||
| 23 | 11 mm | pN1m (1/1) | 0% | INTENSE | x | INTENSE | x | ||||
| 24 | 17 mm | pN1a (2/19) | 0% | INTENSE | x | FOCAL | x | ||||
| 25 | 13 mm | pN3b (20/24) | 0% | INTENSE | x | FOCAL | x | ||||
| ER NEG/LYMPH NODE NEG | |||||||||||
| 26 | 8 mm | 0% | INTENSE | x | NEGATIVE | ||||||
| 27 | 16 mm | 0% | INTENSE | x | FOCAL | x | |||||
| 28 | 13 mm | 0% | INTENSE | x | FOCAL | x | |||||
| 29 | 15 mm | 0% | INTENSE | x | NEGATIVE | ||||||
| 30 | 12 mm | 0% | FOCAL | x | INTENSE | x | |||||
| ALL ER NEG TUMORS VS. ALL ER POS TUMORS P<0.05 FOR ABSENCE OF MEMBRANE LOCALIZATION | |||||||||||
Immunohistochemical analysis of moesin and P-moesin in normal breast tissue, benign breast disease and breast cancers. Negative indicates visible staining in less than 1% of the cells. Focal indicates staining in less than 30% cells. Intense indicates diffused staining throughout the tissue. Membrane (MEM) indicates staining exclusively localized to the cell membrane in more than 90% of the cells; membrane/cytoplasm (MEM/CYTO) indicates staining both on the cell membrane as well as in the cytoplasm in more than 90% of the cells; cytoplasm (CYTO) indicates staining of the cytoplasm without any evident membrane staining in more than 90% of the cells. Staining patterns were independently adjudicated by two pathologists. SIZE indicates the diameter of the mammary node. pNx indicates the number of positive lymph nodes. ER% indicates the percentage of tumor cells expressing ERs.