Table 2.

Comparison of performance of fmincon and LINDO solver for estimation of feasible ranges.

		Solver
Computation time for	Ranges to estimate	fmincon	LINDO
- parsing		20 ± 1 s	20 ± 1 s
- feasibility check	1	25 ± 3 s	0.2 ± 0.1 s
- ranges of concentrations	166	51 min	23 s
- ranges of ΔrG	147	145 ± 20 min	30 s
- non-linear constraints	7	n.d.a	1 s

The time is given for at least duplicate analyses of the Schaub data set on a Pentium IV 3 GHz processor. Note: ^a, no runtime is provided because no robust optimization was possible (see text).