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. 2002 Jan 21;86(2):263–268. doi: 10.1038/sj.bjc.6600033

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Copyright © 2002 The Cancer Research Campaign

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.

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Immunocytochemical analysis of p73 and p14^ARF in cervical epithelium. Sections were prepared from formalin-fixed, parrafin- embedded tissue samples as described in Materials and Methods. (A) Expression of p73 is in the basal layer of normal cervical epithelium. RT–PCR analysis revealed that this was full-length, p73α in all cases studied. (B) p73 protein is over-expressed in cervical SCC. RT–PCR analysis revealed expression of both full-length and p73 Δ2 in the majority of cases. (C) p14^ARF protein expression is not detectable in normal cervical epithelium. (D) Over-expression of p14^ARF in cervical SCC. Note the prominent nucleolar expression and sparing of normal tissue.