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. 2002 Mar 4;86(5):737–743. doi: 10.1038/sj.bjc.6600153

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Copyright © 2002 Cancer Research UK

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RT–PCR-amplification (A) and relative (GAPDH-normalised) mRNA levels (B) of survivin variants in paired samples of non-neoplastic (N) and neoplastic (T) gastric tissue. (A) In eight out of 14 non-neoplastic tissue samples, no or barely detectable levels of survivin mRNA levels were observed. In each cancer tissue sample, survivin expression level exceeded that of the corresponding non-neoplastic tissue sample. GAPDH served as internal control. (B) Expression of survivin and survivin-2B – but not survivin-ΔEx3 - are elevated in gastric carcinomas. Two-tailed P-values were calculated by the Mann–Whitney-test.