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. 2002 Apr 22;86(8):1348–1354. doi: 10.1038/sj.bjc.6600225

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Copyright © 2002 Cancer Research UK

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Uptake and conversion of 10 μM compounds 1a to 1 in: (A) inherently insensitive A498 renal cells and (B) sensitive ER+ T47D breast cells. Compound 1a is rapidly and efficiently hydrolysed by both cell lines. Only sensitive cells (B) sequester regenerated compound 1.