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. 2002 Apr 22;86(8):1348–1354. doi: 10.1038/sj.bjc.6600225

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Copyright © 2002 Cancer Research UK

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Mean GI₅₀ graph demonstrating the selective nature of growth inhibition by (A) compound 2 and (B) compound 2b in the NCI in vitro panel of human derived cancer cell lines. Cells were exposed to drug for 48 h before viability was determined using the sulforhodamine B assay. Display of data utilises the mean graph format where the average GI₅₀ concentration is plotted on the centre line. Using a log scale, the sensitivity or resistance of a particular cell line is represented by deflections to the right or left, respectively, from the mean.