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. 2002 Jun 17;86(12):1963–1969. doi: 10.1038/sj.bjc.6600355

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Copyright © 2002 Cancer Research UK

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The addition of exogenous IGFBP-3 overcomes TGF-β-induced growth inhibition of MCF-10A cells. Graph shows the per cent of cells relative to the control. MCF-10A cells were treated with TGF-β (5 ng ml⁻¹) for 3 days with or without IGFBP-3 (50 ng ml⁻¹) added on each of the 3 days or IGFBP-3 (150 ng ml⁻¹) added only on day 1 with TGF-β, (where **IGFBP-3 (50 ng day⁻¹)+TGF-β>TGF-β; P<0.01, *TGF-β<CT; P<0.05). Graph represents the mean of experiments that were each performed in triplicate at least three times.

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