Table 1.
Developmental changes in properties of synaptic connections and input resistance
Age | P14–16 | P17–20 | P24–29 |
---|---|---|---|
Unitary EPSP (mV) | 1.11 ± 1.01 (n = 29) | 1.24 ± 1.28 (n = 27) | 0.65 ± 0.77 (n = 24)* |
Coefficient of variation | 0.38 ± 0.20 (n = 29) | 0.30 ± 0.16 (n = 26) | 0.54 ± 0.20 (n = 24)** |
Failure rate (%) | 2.39 ± 4.08 (n = 29) | 1.44 ± 3.29 (n = 22) | 10.61 ± 8.68 (n = 22)** |
PPR (%) (EPSP2/EPSP1× 100) | 70.1 ± 16.6 (n = 16) | 82.6 ± 10.8 (n = 17)* | 103.8 ± 32.5 (n = 21)** |
PPR (%) (EPSP3/EPSP1× 100) | 60.2 ± 15.7 (n = 16) | 66.9 ± 10.9 (n = 17) | 98.3 ± 29.8 (n = 21)** |
20–80% Rise time (ms) | 1.84 ± 0.48 (n = 19) | 1.35 ± 0.54 (n = 23)* | 1.61 ± 0.36 (n = 11) |
Decay time constant (ms) | 25.9 ± 6.9 (n = 19) | 17.8 ± 4.5 (n = 18)** | 20.4 ± 7.4 (n = 12)* |
Latency (ms) | 1.24 ± 0.44 (n = 16) | 1.07 ± 0.40 (n = 20) | 1.15 ± 0.45 (n = 9) |
Input resistance (MΩ) | 144 ± 57 (n = 37) | 90 ± 30 (n = 33)** | 83 ± 28 (n = 28)** |
Asterisks indicate statistically significant difference from the P14–16 age group (
P < 0.05,
P < 0.005).