Figure 5. Heat enhances the sensitivity and efficacy of voltage activation for TRPV1.
A, representative current traces in response to a family of voltage steps at 25°C and 32°C in the absence or presence of protons (pH 6.0). B, Boltzmann fits to the conductances obtained from steady state currents at the end of the pulse. C, summary of the V1/2 values at the given temperatures (n = 4–5). D, summary of the fractional Gmax normalized to pH 6.0 (n = 4–5). *P < 0.05 **P < 0.005. Data were compared to 20°C.