Figure 1. Suction pipette recordings of mouse olfactory receptor neurons.

Fast wild-type (A) and slow OMP^−/− ORN (B) responses were recorded in response to a 2 s 100 μm cineole stimulation. C and D, suction pipette currents elicited by the phosphodiesterase inhibitor IBMX (1 mm for 1 s) in an OMP-positive and -negative ORN. All traces are filtered DC to 50 Hz to display the receptor current alone. E–F, the same recordings as in A–D at an expanded time scale, but filtered at DC to 5000 Hz to investigate action potential firing. The solution monitor at the top indicates the timing of the command pulse which initiated the solution change; the actual solution change occurred with a slight delay (see Methods).