Figure 5. Interaction of LTP and STP.

A, distributions of amplitude gains in a single experiment (upper panels) and pooled data (lower panels; n = 8 experiments with 3 different stimulus trains) differ remarkably before (left) and after the induction of LTP (right). B, gains of response amplitudes during the stimulus train are decreased after induction of LTP. The dynamic range of responses is significantly reduced, both in a single experiment and the summary of several analogue experiments (corresponding data to A). C, the amount of short-term potentiation after LTP induction is related to the corresponding response amplitude before LTP. Initially small responses are increased, whereas initially large ones are less potentiated or even slightly depressed as seen in single experiment (upper panel) and the summary of n = 7 analogue experiments (lower panel; mean ± s.d.). Amplitudes are normalized to the mean response amplitude during stimulus train in control condition.