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. 2007 Nov 15;586(Pt 1):175–184. doi: 10.1113/jphysiol.2007.147470

Figure 3. FDB fibres overexpressing SOD2 are more fatigue resistant than WT fibres.

Figure 3

A, Western blot analysis of SOD2 levels in heart, brain and skeletal muscle of SOD2 overexpressing and WT mice. B, the force–frequency (top) and [Ca2+]i–frequency (bottom) relationships in SOD2 overexpressing (•) and WT (○) FDB fibres. C, tetanic force (top) and [Ca2+]i (bottom) during fatigue induced by repeated tetanic stimulation. Data are means ± s.e.m. (n = 4) and values obtained in 70 Hz tetani produced under control conditions were set to 100% in each cell. *P < 0.05 and **P < 0.01 SOD2 overexpressing versus WT fibres.