Figure 6. Effects of 7 days of functional overload (FO) and the absence of a functional IGF-I receptor on changes in p70^s6k phosphorylation (Thr389).

WT and MKR refer to muscle masses measured from control animals, while WT-7d FO and MKR-7d FO refer to mice subjected to functional overload surgery for 7 days. No differences were detected in total p70^s6k from any group (data not shown). *Statistically different from the control for WT and MKR mice (P < 0.05). (WT n = 3; WT-7d FO n = 3; MKR n = 3; MKR-7d FO n = 3.)