Table 2.

TMS measures of motor cortical excitability before (pre) and after (post) a single oral dose of PBO, DZP or BAC

Measure	pre-PBO	post-PBO	pre-DZP	post-DZP	pre-BAC	post-BAC
RMT left M1 (%)	38.4 ± 2.2	38.0 ± 2.0	37.9 ± 1.2*	40.3 ± 1.5*	39.9 ± 2.5	41.0 ± 2.9
RMT right M1 (%)	53.8 ± 3.2	53.4 ± 2.7	54.5 ± 2.9	55.3 ± 2.8	54.9 ± 3.1	55.0 ± 3.1
AMT left M1 (%)	30.9 ± 2.3	30.9 ± 2.4	30.5 ± 1.6	31.5 ± 2.0	31.9 ± 2.3	32.4 ± 2.2
AMT right M1 (%)	46.4 ± 3.5	45.5 ± 3.0	47.4 ± 3.7	47.4 ± 3.3	48.3 ± 3.4	48.9 ± 3.2

All values are given as mean ± 1 s.e.m. (n = 8). Both RMT and AMT are given as a percentage of maximum stimulator output. Note that coil orientations and stimulator setup were different for the left and right M1 (see Methods), resulting in higher thresholds over the right M1 in all three sessions (Student's paired two-tailed t tests, P < 0.001 for all comparisons).

^*Indicates significant differences between pre and post measurements (Student's paired two-tailed t test, P < 0.05).