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. 2007 Nov 22;586(Pt 3):899–911. doi: 10.1113/jphysiol.2007.143586

Figure 2. Intermittent hypoxia caused a sustained hypertension that is attenuated in the presence of hyperglycaemia.

Figure 2

A, changes in mean arterial blood pressure over time during saline infusion (intermittent hypoxia, n = 17; intermittent air n = 13; statistical difference determined by one-way ANOVA). B, changes in mean arterial blood pressure over time during glucose infusion (intermittent hypoxia, n = 14; intermittent air n = 14; statistical difference determined by one-way ANOVA). C, averaged changes in mean arterial blood pressure during the light and dark periods for all four experimental groups (note: data for dark period is plotted twice to highlight the diurnal rhythm). Analysis by two-way ANOVA revealed a significant effect of exposure (intermittent hypoxia > intermittent air; P < 0.0001) and infusion (glucose < saline; P < 0.0001), and a significant interaction (glucose infusion reduced the hypertensive effects of intermittent hypoxia exposure; P < 0.05).