Figure 3. Effect of 100 μm 9-AC on twitch and tetanic responses in a skinned EDL fibre with Cl⁻ present.

A, responses to supramaximal single pulse stimuli and trains of pulses at 50 or 100 Hz, before and after addition of 9-AC. Force response to maximum Ca²⁺-activation solution (‘max’) shown at right. Time scale: 2 s for twitch and tetani and 5 s for maximum Ca²⁺ activation. B, tetanic responses from A on an expanded time scale to highlight the fade of the response at 50 and 100 Hz (stimulus timing shown beneath each response).