Figure 5. Cartoon representation of alteration in binding kinetics.
If an ancillary subunit changes the ‘shape’ of the binding site, this will affect the transition rates between the open and drug-bound states.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.