Figure 5.

The concentration dependence of the kinetics of inhibition by competitive antagonists at 37°C The mean and s.d. for onset and recovery rates for (+)-tubocurarine (A), pancuronium (B) and cisatracurium (C) are plotted. The continuous lines were determined by linear regression (onset) or arithmetic mean (recovery). Dashed lines indicate the data at 25°C (Wenningmann & Dilger, 2001). Note how temperature has a stronger effect on the slope of the onset rate for (+)-tubocurarine and pancuronium than for cisatracurium. Numerical results are given in Tables 3 and 4.