Table 2.
Biophysical properties of voltage-gated INa in vagal nodose ganglion neurons
| TTX method | Voltage method | |
|---|---|---|
| TTX-R INa | ||
| Activation | ||
| V1/2 | −15.47 ± 0.72 | −11.70 ± 1.21 |
| k | 4.91 ± 0.17 | 5.70 ± 0.20 |
| n | 39 | 23 |
| Steady-state inactivation | ||
| V1/2 | −32.82 ± 0.73 | — |
| k | 5.55 ± 0.33 | — |
| n | 31 | — |
| TTX-S INa | ||
| Activation | ||
| V1/2 | −26.99 ± 0.99 | −22.57 ± 1.22 |
| k | 5.98 ± 0.30 | 5.69 ± 0.29 |
| n | 33 | 23 |
| Steady-state inactivation | ||
| V1/2 | −77.83 ± 1.03 | — |
| k | 6.31 ± 0.34 | — |
| n | 29 | — |
| NaV1.8 | ||
| V1/2 | −12.6 ± 2.0 | — |
| k | 7.4 ± 0.7 | — |
| n | 17 | — |
| NaV1.9 | ||
| V1/2 | −54.8 ± 2.8 | — |
| k | 4.8 ± 0.7 | — |
| n | 13 | — |