Figure 3. Stimulation of the sodium myo-inositol transporter SMIT1 by SGK isoforms and PKB.
The SGK isoforms 2 and 3 and to a lesser extent the protein kinase B were similarly capable of up-regulating SMIT1 currents in Xenopus oocytes. Arithmetic means ± s.e.m. of myo-inositol (2 mm)-evoked currents. * indicates statistically significant difference (P < 0.05) to oocytes injected with SMIT1 alone.