Figure 6. Kinetics of myo-inositol-evoked currents in SMIT1 expressing Xenopus laevis oocytes.
While coexpression of SGK1 and SGK3 increased Vmax of the carrier (see Table 1 and A), SMIT1 substrate affinities for myo-inositol remained unaffected (see Table 1 and B). Arithmetic means ± s.e.m. of myo-inositol (2 mm)-evoked currents. Data are normalized to the maximum value of the control group (cells solely injected with SMIT) (A) or to maximum value of the respective group injected with SMIT alone, SMIT + SGK1 or SMIT + SGK3 (B).