Figure 1. Schematized drawing of the subcellular topography of Kv7 channel expression in a principal mesencephalic dopaminergic neuron.

Kv7.2-Kv7.5 channels are indicated at different principal subcellular positions where Kv7 channel mRNA and/or protein expression has been reported. Note that the Kv7.4 channels are expressed only in mesencephalic dopaminergic neurons at somatodendritic sites, whereas Kv7.2 and Kv7.3 channels are found at several cellular pre- and postsynaptic locations. Modified from Kandal ER, Jessell TM & Schwartz JH (2000), Principles of Neural Science, McGraw-Hill Medical, reproduced with permission of the McGraw-Hill Companies.