Table 1.
p(t-test) < 0.01 | p(t-test) < 0.05 | p(t-test) < 0.05, FCb>2 | ||||||
Treatment | genes | max. FDRa | genes | max. FDRa | genes, total | up | down | mixed |
1 h | 327 | 0.589 | 1350 | 0.719 | 130 | 98 | 32 | - |
4 h | 524 | 0.307 | 2019 | 0.402 | 532 | 407 | 125 | - |
8 h | 1476 | 0.068 | 4576 | 0.110 | 1805 | 1246 | 559 | - |
24 h | 854 | 0.173 | 3124 | 0.238 | 1154 | 658 | 496 | - |
In at least 1 time point | 2830 | - | 8471 | - | 2881 | 1854 | 1007 | 20 |
p(ANOVA) < 0.01 | p(ANOVA) < 0.05 | p(ANOVA) < 0.05, FCc>2 | ||||||
Treatment | genes | max. FDRa | genes | max. FDRa | genes | |||
All | 1756 | 0.084 | 4093 | 0.169 | 3111d |
a the highest expected false discovery rate (FDR); i.e. the maximal q-value observed for the given p(t-test) cut-point
b fold-change between treatment and control
c maximum fold change between treatments [max (treatment/control)/min (treatment/control)]
d of these 3111 genes only 1686 genes are also among the group of 2881 genes that are differentiallyexpressed in at least one time point with p(t-test) < 0.05 and FCb > 2