Figure 6.

Predictions of the stress-fibre distributions in a circular cell of radius R=17.5 μm on a circular ligand patch of equal radius. Steady-state distributions of Γ (a) after application of an anisotropic activation signal that constrains stress-fibre formation to $\left|\varphi \right|\le 10°$ and (b) after a second isotropic activation signal is applied to the cell with the initially anisotropic stress-fibre distribution shown in (a). (c) The control case of the steady-state distributions of Γ after the application of two isotropic activation signals. The direction ϕ_S is indicated by line segments having length scaled by Γ in all cases.