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. 2008 May 6;2008:716458. doi: 10.1155/2008/716458

Figure 4.

Figure 4

ICAM-1 immunohistochemistry in the injured cortex in SHAM group (n = 5), TBI group (n = 6), and TBI-NAC group (n = 6). (a) SHAM rats showing few ICAM-1 positive vessels. (b) TBI rats showing strong ICAM-1 positive vessels stained as brown. (c) TBI-NAC rats showing less ICAM-1 positive vessels than TBI rats (scar bar, 50 μm). (d) Administration of NAC remarkably inhibited TBI-induced upregulation of ICAM-1 expression on cerebrovascular endothelia. **P < .01 versus SHAM group; # P < .05 versus TBI group.