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. 2008 May 6;2008:716458. doi: 10.1155/2008/716458

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Copyright © 2008 Gang Chen et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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TUNEL immunohistochemistry staining of the injured cortex in SHAM group (n = 5), TBI group (n = 6), and TBI-NAC group (n = 6). (a) SHAM group rats showing few TUNEL apoptotic cells. (b) TBI group rats showing more TUNEL apoptotic cells stained as brown. (c) TBI-NAC group rats showing less TUNEL apoptotic cells than TBI group (scar bar, 50 μm). (d) Administration of NAC significantly decreased the apoptotic index in rat injured brain following TBI. **P < .01 versus SHAM group; ^## P < .01 versus TBI group.