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Hypersensitivity of FANCD2-deficient human fibroblasts to DNA damage. (a) Clonogenic survival of cells with or without wild-type FANCD2 (PD20-wtD2 or PD20, resp.) after treatment with varying concentrations of MMC for one hour. (b) Analogously, clonogenic survival after exposure to hydrogen peroxide (H2O2) for two hours. Data represent logarithmic means +/− standard error based on four independent repeats.
