Figure 1.

Schematic representation of Blast2GO application. GO annotations are generated through a 3-step process: blast, mapping, annotation. InterPro terms are obtained from InterProScan at EBI, converted and merged to GOs. GO annotation can be modulated from Annex, GOSlim web services and manual editing. EC and KEGG annotations are generated from GO. Visual tools include sequence color code, KEGG pathways, and GO graphs with node highlighting and filtering options. Additional annotation data-mining tools include statistical charts and gene set enrichment analysis functions.